Regulation of cell-substrate adhesion by proteoglycans immobilized on extracellular substrates
نویسندگان
چکیده
منابع مشابه
Regulation of cell-substrate adhesion by proteoglycans immobilized on extracellular substrates.
We have demonstrated previously that chick embryo fibroblasts synthesize and secrete a large chondroitin sulfate proteoglycan (designated PG-M) that binds to fibronectin. We now report the possibility that PG-M interactions with cell surfaces can modulate cell-substrate adhesion. When PG-M was added to the medium, various types of trypsinized cells failed to adhere not only to fibronectin-coate...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1989
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)83143-x